March 10, 2015 - The U.S. Court of Appeals for the Third Circuit affirmed the decision of the district court.
December 20, 2013 - The lead plaintiffs filed a notice of appeal.

December 2, 2013 - The court ordered the second amended complaint dismissed with prejudice and ordered the case closed.

October 21, 2013 - The court granted the defendants motion to dismiss and with leave to file a motion for leave to file a third amended complaint.

August 9, 2013 - The defendants filed a motion to dismiss.

July 11, 2013 - The lead plaintiffs filed a second amended consolidated complaint.

June 11, 2013 - The court granted defendants' motion to dismiss without prejudice. The court dismissed the case with leave to amend.

August 14, 2012 - Defendants filed a motion to dismiss.

June 8, 2012 - The lead plaintiffs filed an amended consolidated complaint.

May 9, 2012 - Lead plaintiff and lead counsel were appointed and all cases were consolidated.

April 2, 2012 - Lead plaintiff motions were filed.

February 1, 2012 - An investor in shares of Columbia Laboratories Inc (NASDAQ: CBRX) filed a lawsuit in the U.S. District Court District of New Jersey against Columbia Laboratories Inc over alleged Violations of Federal Securities Laws in connection with certain statements concerning Columbia Laboratories’ progesterone vaginal gel.

According to the complaint the plaintiff alleges on behalf of all persons or entities who purchased Columbia Laboratories Inc (NASDAQ: CBRX) securities between December 6, 2010 and January 20, 2012, that Columbia Laboratories Inc and certain of its officers violated the Securities Exchange Act of 1934 by issuing allegedly materially false and misleading statements. Specficially the plaintiff alleges that Columbia Laboratories Inc conditioned investors to believe that Columbia Laboratories’ PROCHIEVE progesterone vaginal gel 8% , a gel intended to prevent preterm births in women with short cervices, would receive Food and Drug Administration (“FDA”) approval through a host of statements regarding the safety and efficacy of the product, as well as reportedly positive results from PROCHIEVE's clinical trials.

Columbia Laboratories Inc reported that its annual Revenue rose from $29.63million for 2007 to $45.68million for 2010. However, its Net Loss increased over the same time period from $14.29million to $21.83million.

Shares of Columbia Laboratories Inc (NASDAQ: CBRX) rose from as low as $0.82 per share in November 09 to slightly over $4 per share in April 2011.

Then on December 14, 2011, Columbia Laboratories Inc announced that a meta-analysis of data from five double-blind, placebo-controlled trials its progesterone gel product significantly reduces the risk of preterm birth and neonatal morbidity.

However on January 17, 2012 a report by the Food and Drug Administration staff about Columbia Laboratories Inc progesterone gel to reduce the risk of preterm birth was released. According to the report Columbia Laboratories Inc’s progesterone gel wasn’t effective.

Shares of Columbia Laboratories Inc (NASDAQ: CBRX) fell from slightly below $3 on January 10, 2012 to as low as $1.05 per share on January 17, 2012.

On January 20, 2012, Columbia Laboratories Inc (NASDAQ: CBRX), and Watson Pharmaceuticals Inc (NYSE: WPI) confirmed that the Advisory Committee for Reproductive Health Drugs of the U.S. Food and Drug Administration (FDA) declined to recommend the approval of progesterone vaginal gel 8% for the reduction of risk of preterm birth in women with short uterine cervical length at the mid-trimester of pregnancy. While panel members generally agreed that progesterone vaginal gel 8% is safe, the panel stated that more information is needed to support approval.

Columbia Laboratories Inc said the final decision regarding the approval of the product rests solely with the FDA and the FDA's Division of Reproductive and Urologic Products is expected to take action on Columbia's New Drug Application (NDA) by February 26, 2012.

On the same day a media report cited advisors to U.S. regulators saying Columbia Laboratories Inc (NASDAQ: CBRX) and Watson Pharmaceuticals Inc (NYSE: WPI) didn’t provide sufficient data that their progesterone gel reduces the risk of preterm birth.

Columbia Laboratories Inc (NASDAQ: CBRX) shares declined an additional $0.874 per share or more than 55%, to close at $0.706 per share on January 23, 2012.